Ingrid Grazielly Felix Araujo
Medical
Student at Centro Universitário Maurício de Nassau, Recife-PE, Brazil; Email:
ingridfaraujo01@gmail.com
Davyson da Silva Areco
Medical
Student at Centro Universitário Maurício de Nassau, Recife-PE, Brazil; Email:
davysonareco@gmail.com
Luiza Cavalcanti Farias
Medical
Student at Centro Universitário Maurício de Nassau, Recife-PE, Brazil; E -mail :
luizacfarias@gmail.com
Ana Beatriz Bezerra Torres
Medical
Student at Centro Universitário Maurício de Nassau, Recife-PE, Brazil; Email:
beatrizbtorres@hotmail.com
Leonardo Antônio Cavalcanti Lira
Medical
Student at Centro Universitário Maurício de Nassau, Recife-PE, Brazil; Email:
leo.cavalcanti.lira@gmail.com
Maria Helena Queiroz de Araújo
Mariano
Rheumatologist and professor at the Maurício de Nassau University
Center,
Recife-PE,
Brazil;
Email:
habhelena58@gmail.com
ABSTRACT
Introduction and Objective : This study aimed to carry out a
literature review on the cardiac manifestations of ankylosing spondylitis (AS).
Methods : A bibliographic survey was
carried out between 2011 and 2021, in the PUBMED and SciELO databases. The
descriptors were used: Spondyloarthritis, Ankylosing Spondylitis, Cardiac
manifestations, and Cardiovascular manifestations, resulting in 21 studies,
after reading the abstracts, only 13 were selected, which addressed the cardiac
involvement of the disease. Results :
The literature points out that due to its inflammatory pattern and
chronification, extra-articular manifestations can be observed in some patients
with AS. In these outcomes, it is worth noting cardiac conduction disorders.
The incidence of cardiovascular involvement in patients with AS is more
commonly reported in 10-30% of these individuals with the disease. Valve
involvement is present, the most reported aortic, with greater sensitivity and
specificity for AS. Such involvements cannot be monitored only by inflammatory
tests, such as erythrocyte sedimentation rate (ESR) and c-reactive protein
(CRP), since there is no uniform character in the evolution of AS and its
extra-articular conditions. Conclusion :
The extra-articular manifestations in AS, although rare, are indicative of a
worse prognosis for patients with carriers and, consequently, present high
morbidity, therefore, they should be diagnosed and treated early to increase
the chances of a better prognosis for these individuals.
Keywords: Ankylosing Spondylitis. Cardiovascular diseases. HLA-B27 antigen.